Download e-book for iPad: Arterial Disorders: Definition, Clinical Manifestations, by Adel Berbari, Giuseppe Mancia

By Adel Berbari, Giuseppe Mancia

ISBN-10: 331914555X

ISBN-13: 9783319145556

ISBN-10: 3319145568

ISBN-13: 9783319145563

As our wisdom approximately arterial ailment is enormously increasing, the purpose of this ebook is to discover all points of arterial pathology, together with class, scientific manifestations, pathogenesis, and healing strategies. The dialogue of pathophysiologic mechanisms of arterial disorder is vast ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental components. specific emphasis is put on fresh suggestions, corresponding to: the position of age-associated arterial changes within the initiation and development of cardiovascular ailments in older individuals, the significance of mineral metabolism-bone vascular interactions, the scientific and prognostic value of the renal resistive index, retinal move, toxemia of being pregnant as an arterial ailment, and the function of pulmonary/vascular interplay in pulmonary high blood pressure and cross-talk of macrocirculation and microcirculation in goal organ involvement. overview strategies are conscientiously defined, and the total diversity of at present to be had healing ideas, together with way of life variations and pharmacologic methods, are defined and appraised. ​

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Additional resources for Arterial Disorders: Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches

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Ben-Shlomo Y, Spears M, Boustred C et al (2014) Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects. J Am Coll Cardiol 63:636–646 47. Vlachopoulos C, Aznaouridis K, O’Rourke MF et al (2010) Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and metaanalysis. Eur Heart J 31:1865–1871 48. Chirinos JA (2013) Ventricular-arterial coupling: invasive and non-invasive assessment.

Circ Res 76:132–141 27. O’Rourke MF, Nichols WW (2005) Aortic diameter, aortic stiffness, and wave reflection increase with age and isolated systolic hypertension. Hypertension 45:652–658 28. Wagenseil JE, Mecham RP (2009) Vascular extracellular matrix and arterial mechanics. Physiol Rev 89:957–989 29. Vanhoutte PM, Rubanyi GM, Miller VM, Houston DS (1986) Modulation of vascular smooth muscle contraction by the endothelium. Annu Rev Physiol 48:307–320 30. Schlatmann TJ, Becker AE (1977) Histologic changes in the normal aging aorta: implications for dissecting aortic aneurysm.

Noninvasive assessment of central aortic pressure can now be achieved using highfidelity applanation arterial tonometry at the carotid artery or by using a generalized transfer (GTF) function to synthesize an aortic pressure waveform from the radial (or brachial) pressure waveform [3, 66, 67]. Pulsatile aortic blood flow can also be measured noninvasively in humans, using pulsed wave Doppler ultrasound [68–70] or phase-contrast magnetic resonance imaging [71]. The most convenient method to assess aortic inflow is pulsed wave Doppler interrogation of the LV outflow tract, given that systolic LV volume outflow equals proximal aortic volume inflow [70].

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Arterial Disorders: Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches by Adel Berbari, Giuseppe Mancia


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