By Valentin Fuster MD PhD, Eric J. Topol MD, Elizabeth G. Nabel MD
Written by way of the world’s most well known experts, this quantity presents accomplished assurance of present ways to the prevention, analysis, and administration of atherothrombosis and its coronary and noncoronary issues. This version has been completely up to date, sharply fascinated by scientific info, and trimmed to at least one attainable volume.
Coverage starts with a evaluate of danger elements and prevention, emphasizing lipid abnormalities, high blood pressure, smoking, diabetes, and weight problems. next sections research the pathogenesis of atherosclerosis, markers and imaging, acute coronary syndromes, continual good angina, and noncoronary atherothrombosis. scientific displays, clinical administration, and the newest interventional options are included.
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Additional resources for Atherothrombosis and coronary artery disease
As a result, the attributable risk and the potential benefit of treatment increases with age (11). In the elderly, average total and atherogenic LDL-cholesterol often are unacceptable and are greater in women than men.
Although the popularity of therapeutic bleeding had declined by the late 1860s, some doctors still used the procedure in angina because it was thought to reduce arterial tension. When Brunton bled patients with GW_Fuster_CH001_0001-0014 9/23/04 12:42 PM Page 9 HISTORICAL PERSPECTIVE / 9 Regius Professor of Medicine at Cambridge and a prolific author, published several articles on angina and, until his death in 1925, held steadfastly to the belief that it was caused by disease of the aortic root.
Burns drew an analogy between coronary artery disease and the ligation of a peripheral artery to support his view of the pathophysiology of angina pectoris (29). Although the contributions of Jenner, Parry, and Burns seemed to document a relation between coronary artery disease and angina pectoris, other observations made during the nineteenth century undermined the coronary theory of angina. For example, in his 1813 book on dropsy, a condition now known usually to be caused by congestive heart failure, British physician John Blackall described one patient with typical angina who had only trivial coronary artery disease, but whose ascending aorta was severely atherosclerotic.
Atherothrombosis and coronary artery disease by Valentin Fuster MD PhD, Eric J. Topol MD, Elizabeth G. Nabel MD